THE INFLUENCE OF DEFICIENCY OF MICROELEMENTS IN CHILDREN WITH BRONCHIAL HYPERREACTIVITY

Raufov A.А., Naimova Sh.А.

Email: Raufov6102@scientifictext.ru

Raufov Alisher Anvarovich - Assistаnt;

Naimova Shohida Anvarovna – Assistant,

DEPARTMENT OF FACULTY AND HOSPITAL THERAPY,

BUKHARA STATE MEDICAL INSTITUTE,

BUKHARA, REPUBLIC OF UZBEKISTAN

Abstract: the study shows pathogenetic mechanisms of formation of bronchial hyperreactivity associated with microelementosis. The study group consisted of 58 children with a combination of atopic dermatitis and bronchial asthma. Methods: inhalation-provocation tests with histamine and metacholine, atomic absorption spectrometry, x-ray fluorescence method. The state of hyperreactivity of the bronchi was accompanied by a deficit of essential microelements (69.6 %) with high sensitivity of the bronchi (PK20 metacholine, histamine-0.125-0.5 mg/ml), against the background of selenium and zinc deficiency (plasma content below 0.2 and 0.35 mg/l, respectively), reducing the speed parameters of the external respiratory function.

Keywords: hyperreactivity of the bronchi, microelementoses, atopic dermatitis, bronchial asthma.

ВЛИЯНИЕ ЗАЩИТЫ МИКРОЭЛЕМЕНТОВ У ДЕТЕЙ С БРОНХИАЛЬНОЙ ГИПЕРРЕАКТИВНОСТЬЮ

Рауфов А.А., Наимова Ш.А.

Рауфов Алишер Анварович - ассистент;

Наимова Шохида Анваровна – ассистент,

кафедра факультетской и госпитальной терапии,

Бухарский государственный медицинский институт,

г. Бухара, Республика Узбекистан

Аннотация: в исследовании показаны патогенетические механизмы формирования гиперреактивности бронхов, ассоциированной с микроэлементозом. Группу исследования составили 58 детей с сочетанием атопического дерматита и бронхиальной астмы. Методы: ингаляционно-провокационные пробы с гистамином и метахолином, атомно-абсорбционная спектрометрия, рентгенофлуоресцентный метод. Состояние гиперреактивности бронхов сопровождалось дефицитом эссенциальных микроэлементов (69,6%) с высокой чувствительностью бронхов (метахолин PK20, гистамин-0,125-0,5 мг/мл) на фоне дефицита селена и цинка (содержание в плазме крови) ниже 0,2 и 0,35 мг/л соответственно), снижая скоростные параметры функции внешнего дыхания.

Ключевые слова: гиперреактивность бронхов, микроэлементозы, атопический дерматит, бронхиальная астма.

References / Список литературы

Adizova N.N., Tilloeva Sh.Sh. Condition of right diseases of the heart and pulmonary hypertension in patients with bronchial asthma, complex treatment effects // Special edition for 1st Bukhara international medical students conference, 2019. Р. 9.
Alyavi A.L., Rakhimova D.A., Tilloeva S.Sh., Sabirjanova Z.T. Ventilation- perfusion ability of the lungs and pulmonary hemodynamics in the dynamics of treatment with nebivolol in bronchial asthma with pulmonary hypertension // International Journal of Scientific Research And Education, 2019. Vol. 07. Issue 02. P. 72-75.
Alyavi A.L., Rakhimova D.A., Tilloeva S.Sh., Sabirjanova Z.T., Tukhsanova Z.I. Effects of complex therapy in patients with bronchial asthma and pulmonary hypertension. The relationship of endothelium disorders vasodilation dependent and lung ventilation function // International scientific and practical conference "Innovative ideas of modern youth in Science and education", 2019. P. 73-75.
Aslonova I.J., Yuldasheva D.H., Shadjanova N.S. The occur degree of the bronchoobstructive syndrome's dependence to the hue of the refluxate in the gastroesophageal // International Journal of Bio-Science and Bio-Technology, 2020. № 6. P. 12-18.
Akhmedov M.A., Shamsiev A.M. Acute dilation of the stomach in a 13-year-old child // Vestnik khirurgii imeni II Grekova, 1970. Т. 105. № Р. 82.
Davlatov S.S. et al. Plasmopheresis in the treatment of cholemic endotoxicosis // Academic Journal of Western Siberia, 2013.Vol. 9. № 1. Р. 30-31.
Gafforov S.A., Nurov N.B., Nurova Sh.N. Diagnosis, prevention and treatment of dental anomalies in children with chronic tonsillitis and chronic bronchitis” // Journal of Biomedicine and Practice, 2019. № 4. Р. 71-81.
Juraeva Kh.I., Badridinova B.K. The relationship of causal factors to exacerbation of bronchial asthma.// The Pharma Innovation, 2020. № 9 (6). Р. 311–313.
Ikramova Sh.A., Khamidova. Z.N. Incidence of bronchial asthma in the population of the Вukhara region. Еuropean journal of pharmaceutical and medical research // An International Peer Reviewed Journal for Pharmaceutical, Medical Biological Sciences, 2020. № 8. Р. 234-238.
Inoyatova F.I., Yusupalieva G.A., Inogamova G.Z. Doppler Examination Informativity in Children with Chronic Viral Hepatitis //Detskie Infekcii (Moskva), 2015. Т. 14. № 3. Р. 60-64.
Rakhimova D.А, Tilloeva Sh.Sh., Husenov O.N., Kozilova N.A. Estimation of the condition of the cardiorespiratory system of patients with the concilation of bronchial asthma and arterial hypertension, effects of complex therapy // New day in medicine, 2020. № 2.230. Р. 227-231.
Rakhimova D.A., Tilloeva S.Sh. Study a comparative analysis of the relationship between disorders quality of life and psychoemotional status of patients at different steps of severity of bronchial asthma relating to arterial hypertension and efficiency of various modes of complex therapy // Asian Journal of Multidimensional Research. Reviewed International Journal (AJMR), Vol. 8. Issue 10. P. 5-10.
Kasymov S.Z., Davlatov S.S. Hemoperfusion as a method of homeostasis protection in multiple organ failure syndrome // Academic Journal of Western Siberia, 2013. Vol. 9. № 1. Р. 31-32.
Kasimov S. et al. Нaemosorption In Complex Management Of Hepatargia: o27 (l1-1) // The International Journal of Artificial Organs., 2013. Т. 36. № 8.
Mamatkulov A. et al. Detection of Q-fever in Samarkand region of Uzbekistan: mite surveillance study // International Journal of Infectious Diseases, 2019. Т. 79. Р. 141.
Navruzova Sh.I., Achilova D.N. Cytokine status and humoral immunity depending on the recurrence rate of obstructive bronchitis in children // American Journal of Medicine and Medical Sciences, 2019. 11(12): 523-526. DOI: 10.5923/j.ajmms. 2019. 1112.16.
Shamsiyev A.M., Khusinova S.A. The Influence of Environmental Factors on Human Health in Uzbekistan // The Socio-Economic Causes and Consequences of Desertification in Central Asia. Springer, Dordrecht, 2008. Р. 249-252.
Yusupalieva G.A., Ismailov U.S. Organization of assistance and training of healthcare personnel in medical facilities responding to COVID-19 // Asian Pacific Journal of Environment and Cancer, 2020. Т. 3. № S1. С. 17-19.
Yuldasheva D.H., Аslonova I.J., Shadjanova N.S. The occur degree of the bronchoobstructive syndrome’s dependence to the hue of the refluxate in the gastroesophageal reflux disease// International Journal of Bio-Science and Bio-Technology. Koreya, 2020. № 12. Р. 81-85.
Yuldasheva D.H., Shadjanova N.S., Gulomova SH.К., Abidova I.H. Тhe occur degree of the bronchoobstructive syndrome’s dependence to the hue of the refluxate in the gastroesophageal reflux disease// Journal of research in health science. Israel, 2020. № 4. Р. 78-81.

Ссылка для цитирования данной статьи

Тип лицензии на данную статью – CC BY 4.0. Это значит, что Вы можете свободно цитировать данную статью на любом носителе и в любом формате при указании авторства.

Электронная версия. Raufov A.А., Naimova Sh.А. THE INFLUENCE OF DEFICIENCY OF MICROELEMENTS IN CHILDREN WITH BRONCHIAL HYPERREACTIVITY // Вестник науки и образования № 24(102), 2020 [Электронныйресурс].URL: http://scientificjournal.ru/images/PDF/2020/102/the-influence-of-deficie.pdf (Дата обращения:ХХ.ХХ.201Х).

Печатная версия. Raufov A.А., Naimova Sh.А. THE INFLUENCE OF DEFICIENCY OF MICROELEMENTS IN CHILDREN WITH BRONCHIAL HYPERREACTIVITY // Вестник науки и образования № 24(102), 2020, C. {см. журнал}.